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BMS-708163
Description of:BMS-708163
BMS-708163 is a γ-secretase inhibitor (GSI) (IC50 =0.3 nM)
Theoretical analysis:BMS-708163
M.Wt...
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LY411575
Description of:LY411575
LY411575 is a selective, cell permeable, small molecule gamma secretase inhibitor with an IC50 of 0.1 nM for APP23 and ...
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DAPT
Description of:DAPT
DAPT is inhibitor of γ-secretase. DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal...
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RO4929097
Description of:RO4929097
RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.
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MK-0752
Description of:MK-0752
MK-0752 is a potent gamma secretase (γ-secretase) inhibitor in clinical development with an IC50 of 5 nM for A&bet...
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Chromatin/Epigenetics
β-catenin
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